Don't stay in a hotel that has a drain between the toilet and the bathtub.
The possible reason for such a drain placement.
1) This bathroom is prone to flooding (to bad if you're in room #401)
2) At some point they figure this bathroom is going to flood (again, to bad if you're in room #401)
3) The drunk and incompetent plumber couldn't sober up long enough to place the drain in the bathtub.
Here's the previous tips "LINK"